Premarin Vaginal cream is a mixture of estrogens (a female sex hormone). As a part of the hormone replacement therapy, it works by maintaining the estrogen levels in the body in menopausal women. It also prevents the vaginal wall from becoming thin and dry thereby reducing inflammation.
Premarin Vaginal cream should be applied all over the vagina as per the provided instructions by the doctor. Even if your symptoms improve, you should continue the treatment as it has been prescribed.